Cloudflare CDN

php values post_max_size and upload_max_filesize must both be within  Cloudflare's upload limit (see Cloudflare upload limit):

upload size (HTTP POST request size) per plan type:

100MB Free and Pro

200MB Business

500MB Enterprise by default (contact Customer Support to request a limit increase)

If you aren't able to change these settings on your hosting service, please use the "Limit max_post_max_size (MB)" in the WP Media Uploader app's sidebar / More / Advanced menu. Me Up will adjust the upload_max_filesize if it exceeds  post_max_size.

Once you have these values set, Me Up will take care of uploading files that exceed the Cloudflare upload limit.